The complex non-linear behavior of PCR, which makes it such a powerful tool, is also its Achilles' heel. The exponential nature of PCR makes it extremely sensitive to PCR inhibitors that invalidate the quantification and bias subsequent decisions.

This unstable behavior of PCR hardens the standardization of the technology, the optimization of decisions based on it, and its entrance to routine procedures in the commercial diagnostics market.

Labonnet's proprietary technology was developed to analyze reaction data from individual PCR samples and disclose samples that deviate in their kinetics. Excluding such samples from the assay improves then the overall results.

KOD  is a computational tool deployed within Kineret that analyses fluorescence data obtained by amplifying DNA in presence of fluorescence dye in real-time PCR device. 
The aim of the analysis is to scrutinize PCR samples and identify those with defective kinetics. Samples with defective kinetics are than flagged to alert the user from potential errors in quantification.

 The computational algorithm behind KOD is different from recently published methods based on comparison of amplification efficiencies or by comparing Ct values between sample replicates. The unique method protected by patent utilizes the principle of recognition of several of geometric characteristics of amplification profile. Similar method as the one employed in vending machine to recognize fake coins.